Savannah Guthrie’s Missing Mom Nancy’s Life Is ‘in Jeopardy,’ Sheriff Admits—After 84-Year-Old Was ‘Taken From Her Home Against Her Will’

"Today" host Savannah Guthrie's missing mother, Nancy, was "taken" from her Arizona home against her will, police have said—after uncovering evidence inside the property that suggests the 84-year-old was "harmed" during the alleged "abduction."

Nancy was reported missing on Sunday around lunchtime after failing to turn up at her usual church service, having last been seen by her loved ones at around 9:45 p.m. the previous night, when she was dropped off at home following a dinner.

At a press conference held Tuesday—more than 48 hours after Nancy's disappearance was reported—Pima County Sheriff Chris Nanos admitted that authorities have made no major breakthroughs in the case, telling reporters that his department has "a lot of work in front" of them.

He admitted that Nancy's life is "in jeopardy," noting that his department, in collaboration with the FBI, is working to pursue any and all leads but conceded they have yet to pull together enough evidence to identify a specific suspect or suspects in the case.

Nanos refused to elaborate on reports that Nancy's pacemaker stopped syncing with her Apple phone and watch in the early hours of the morning on Feb. 1, nor would he confirm sources' claims that blood was discovered in her home.

"Someone's life is in jeopardy," he said during the media briefing. "We've got to find her, and we've got to work hard to do that."

When asked whether he was able to share any information about what Nancy might have been wearing, or what kind of car she might have been traveling in, Nanos said he had none to share. He also confessed that they do not currently know if they are searching for one suspect, or multiple.

The Pima County Sheriff's Department initially revealed that officers had found "gravely concerning" evidence inside Nancy's Tucson, AZ, property during their search and have now stated that they believe the "Today" show star's mother was "taken against her will."

"I think she was abducted," Sheriff Nanos told NBC News. "When you’re taken from your bed and you don’t want to go somewhere, that’s an abduction."

Nanos' department later clarified that he was speaking figuratively and not suggesting that Nancy was taken from her bed at the home.

He added that his officers had found evidence inside the home that suggests Nancy was "harmed" before being removed from the property, but did not provide any other information.

"We know she was harmed at the home, but we don’t know to what extent," he said.

However, law enforcement sources told the Los Angeles Times that blood had been found inside Nancy's home, alongside signs of forced entry. It is not immediately clear who the blood belonged to.

Law enforcement sources told Fox News that Nancy's Apple devices stopped syncing with her pacemaker at around 2 a.m. local time—and they believe this is when she was taken from the home. An Apple Watch was discovered inside the property, which is understood to have been connected to Nancy's pacemaker via Bluetooth.

During an appearance on the "Today" show on Tuesday morning, Nanos stressed the urgency of the situation, describing Nancy's case as a "race against time."

He added that detectives have taken samples of DNA found in the home, noting that they are using them to try and pin down the identity of a suspect who may have entered the property.

"It is a race against time, and I hope that window hasn’t closed," he said. "We took some samples that we hope will have enough profile of a DNA profile that gives us some identification of what we’re looking at."

The 84-year-old is described as being physically frail—and disappeared from her home without medication that she has to take every 24 hours in order to survive. However, she is understood to have had no cognitive impairments and is described as being "of sound mind."

Savannah, who had been due to fly out to Milan to begin coverage of the Winter Olympics when she received the call alerting her to her mother's disappearance, issued a plea to her fans and followers for "prayers" on Monday night.

In a post shared to her Instagram account, the anchor wrote: "We believe in prayer. We believe in voices raised in unison, in love, in hope. We believe in goodness. We believe in humanity. above all, we believe in Him.

"Thank you for lifting your prayers with ours for our beloved mom, our dearest Nancy, a woman of deep conviction, a good and faithful servant. Raise your prayers with us and believe with us that she will be lifted by them in this very moment.

"We need you."

Savannah ended the post with a verse from Isaiah: "He will keep in perfect peace those whose hearts are steadfast, trusting in the Lord," before writing, "Bring her home."

The "Today" host is understood to have "immediately scrambled" to fly to Tucson after learning of her mother's disappearance, according to CNN.

Police are now offering a $2,500 reward to anyone who is able to provide images, videos, or information that leads to the arrest of Nancy's alleged abductor.

Savannah, 54, was absent from Monday's episode of the "Today" show but issued a statement via her co-hosts, Craig Melvin and Sheinelle Jones, thanking viewers for their messages of support—and urging anyone with any information about her mother's whereabouts to contact local authorities in Pima County.

"On behalf of our family, I want to thank everyone for the thoughts, prayers and messages of support," the statement began. "Right now, our focus remains on the safe return of our dear mom.

"We thank law enforcement for their hard work on this case and encourage anyone with information to contact the Pima County Sheriff’s office at 520-351-4900."

Sheriff Nanos had confirmed to reporters on Monday that authorities suspect foul play in the case, after previously admitting that officers had been left "gravely concerned" by evidence found inside Nancy's property.

"We do in fact have a crime scene, we do in fact have a crime," he said, per CNN. "We know she didn’t just walk out of there. She did not leave on her own."

According to the Daily Mail, a source close to the Guthrie family revealed that some of the evidence uncovered at the home included Nancy's many personal effects, which had been left behind, including her wallet, keys, ID, and phone.

"It’s not a situation where she voluntarily went away, because she didn’t take any of the things you would normally take if you voluntarily went out," the insider claimed.

Nanos had revealed Sunday that homicide detectives had been called in to work on the case, adding that certain details found inside Nancy's home had given cause for "grave concern" among the attending officers, although he did not give any further information about what had been discovered.

Later on Monday, Savannah's co-star and close friend, Jenna Bush Hager, broke down in tears as she revealed during the final hour of the "Today" show that Nancy is currently without medication that she needs to survive.

According to Today.com, Sheriff Nanos added that his department is particularly concerned for Nancy's welfare because of her age and physical condition, although he noted that she is understood to have full control of her cognitive abilities.

"She has some physical ailments that limit her ability to move around,” Nanos said, later adding: "Miss Guthrie is 84 years old and is not in good physical health."

Multiple law enforcement departments responded to the scene, including homicide detectives, he further revealed, stating: "You don’t typically get the sheriff out at a scene like this, but it’s very concerning what we’re learning from the house.

"I hope we find her safe and sound, but we can’t ignore what’s in front of us."

Missing person posters describe Nancy as being 5 feet 5 inches tall, weighing 150 pounds, with brown hair and blue eyes.

Local authorities are using every tool at their disposal in the search for Nancy, including drones, a helicopter, an airplane, and search-and-rescue dogs. Volunteers are also combing the area surrounding the Guthrie home in search of Savannah's mother.

"We’ve pretty much just thrown everything at this as we can," Nanos added.

Speaking to "Today" early on Monday morning, NBC crime reporter Tom Winter revealed that the FBI has also been brought into the search.

"They’ve enlisted the help of the Customs and Border Protection—obviously, not too far from the border there in Mexico. They have some special resources. The FBI is also aware of this case as well," he said.